29/10/2025

Lip dissolving with hyaluronidase: Myths and reality

Lip augmentation with hyaluronic acid is one of the most popular cosmetic treatments worldwide. However, patients are not always satisfied with the […]
Lips
Lips

Lip augmentation with hyaluronic acid is one of the most popular cosmetic treatments worldwide. However, patients are not always satisfied with the results – whether due to overcorrection, asymmetry, or unwanted side effects. In such cases,  hyaluronidase can help by selectively breaking down the injected hyaluronic acid. But there are many myths and misconceptions surrounding the topic of “dissolving lips.” In this blog post, we clarify what is actually true and which facts are often misunderstood.

What is hyaluronidase and how does it work?

Hyaluronidase is an enzyme that specifically breaks down hyaluronic acid. This substance occurs naturally in the body and is responsible for the gradual degradation of hyaluronic acid over time. In aesthetic procedures, the enzyme is used in a higher concentration to quickly reverse undesirable results. The hyaluronidase is injected into the treated area, where it breaks down the cross-linking of the hyaluronic acid molecules. The body then naturally removes the dissolved particles.

Why is hyaluronidase used for lips?

There are several reasons why someone might choose to have hyaluronic acid dissolved in their lips:

  • Overcorrection:  When the lips look too large or unnatural after treatment.
  • Asymmetries:  If one side is more heavily padded than the other.
  • Nodule formation or hardening:  Irregular hyaluronic acid deposits that are noticeable by touch or sight.
  • Bluish discoloration (Tyndall effect):  If the filler material is injected too superficially, it can cause a bluish tint under the skin.
  • Vascular complications:  In rare cases, incorrect placement of hyaluronic acid can impair blood flow. Hyaluronidase can provide rapid relief in emergencies.
  • Dissatisfaction with the result: Sometimes the aesthetic result does not meet expectations.

Myths about lip augmentation with hyaluronidase

Despite its effectiveness, there are many misconceptions surrounding hyaluronidase. We’ll clear up the most common myths:

Myth 1 – Hyaluronidase breaks down the body’s own hyaluronic acid . Reality: Hyaluronidase primarily affects synthetically injected hyaluronic acid. Studies show that the breakdown of the body’s own hyaluronic acid is minimal and reversible. The body constantly produces new hyaluronic acid, so any losses are quickly compensated for.

Myth 2 – Lips look worse after the procedure than before . Reality: Many people fear that their lips will look sunken or saggy after hyaluronidase treatment. However, this is usually only temporary swelling, as the enzyme also draws some water from the tissue. After one to two weeks, the tissue recovers and returns to its natural state.

Myth 3 – Hyaluronidase works immediately and completely. Reality: While initial effects are visible after a few hours, it can take several days for the hyaluronic acid to be completely broken down. In some cases, multiple treatments are necessary, especially if dense or highly cross-linked hyaluronic acid was used.

Myth 4 – Hyaluronidase is dangerous and causes allergies. Reality: Hyaluronidase is generally safe, especially when administered by experienced physicians. Allergic reactions are extremely rare, particularly when an allergy test is performed before treatment.

Myth 5 – Once dissolved, you can never have filler injected into your lips again . Reality :  After complete dissolution, hyaluronic acid fillers can be injected again. It is recommended to wait at least two weeks to allow the tissue to fully recover.

How does a treatment with hyaluronidase work?

  1. Consultation and information : First, a detailed discussion takes place with an experienced specialist. Expectations, potential risks, and the desired outcome are discussed.
  2. Skin test for allergy risk : In rare cases, hyaluronidase can cause allergic reactions. If there is any uncertainty, a skin test can be performed to rule out an intolerance.
  3. Hyaluronidase injection : The hyaluronidase is injected precisely into the treated area using a fine needle. Depending on the situation, a numbing cream can be applied to minimize any discomfort.
  4. Waiting time and assessment : The first results are often visible after just a few minutes. Most of the filler is broken down within 24 to 48 hours. If necessary, a second session can be performed.
  5. Aftercare and planning of a new lip correction : If desired, a new filler treatment can be performed after the lips have fully regenerated – but not before two weeks have passed.

What side effects can occur?

As with any aesthetic treatment, the use of hyaluronidase also has possible side effects. These include:

  • Temporary swelling or redness
  • Mild pain or burning at the injection site
  • Rare allergic reactions (in cases of intolerance)
  • Unevenness may occur if the hyaluronic acid is not dissolved evenly (however, this can be corrected in a second session).

Most of these side effects subside within a few days. Complications are extremely rare when treated by experienced specialists.

Conclusion: Hyaluronidase as a safe solution for unwanted lip fillers

The option of  lip augmentation offers patients the freedom to quickly correct undesirable results. Hyaluronidase is a proven method that can be used precisely and safely to eliminate asymmetries, overcorrections, or complications.

The fear of negative effects is often unfounded, as long as the treatment is performed by an experienced specialist. Therefore, if you are considering corrective surgery,  competent advice is  the first and most important step.

Do you have questions or would you like a professional assessment? Schedule an appointment at our clinic now  and receive personalized advice from our experts!

Favicon
AUTHOR
InGold Aesthetics
Share
TESTIMONIALS

They say about us

280+ Reviews
5